Download A Clinical Approach to Medicine by Ong Yong Yau, Woo Keng Thye, Ng Han Seong, Patrick Tan, Tang PDF

By Ong Yong Yau, Woo Keng Thye, Ng Han Seong, Patrick Tan, Tang Ong Teng

During this re-creation of A scientific method of medication, the editor has assembled a panel of major clinicians and researchers, and reorganized the fabric within the key parts of medication, cardiology, endocrinology, gastroenterology, hematology, neurology, oncology, rheumatology, renal medication and respiration drugs. This publication is exclusive -- it displays the adventure of major specialists on styles of affliction within the Asia-Pacific area. There are numerous different comparable books, yet these are by means of authors from the West and hence supply a unique viewpoint. The e-book additionally comprises discussions on genetic illnesses, an infection and antimicrobial resistance to antibiotics, highlighting neighborhood incidences and facts. every one bankruptcy begins with the elemental options of a selected subject and progressively develops the subject matter to offer the cutting-edge within the subject. With its concentrate on practices detailed to Asia-Pacific, this booklet is a needs to for the coed, training clinician and learn scientist attracted to the most recent advancements during this a part of the realm.

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Sample text

A detailed discussion of the drug classes is beyond the scope of this review. Drug selection should be predicated on the following considerations: 1) Blood pressure control The overwhelming therapeutic priority is for optimal blood pressure control. The physician must be prepared to use drugs in combination or to change ineffective treatment, if necessary. Combination therapy, especially, has the potential to increase efficacy at lower doses of the individual drugs, thus improving the side-effect profile.

Symptoms include nocturnal snoring, daytime fatigue and somnolence). Detection is by sleep oximetry, or more elaborate polysomnography. Treatment with continuous positive airway pressure — or oral appliances or uvulopalatoplasty for selected patients — may yield substantial blood pressure reduction. 2 mmol/L (unprovoked hypokalemia) or excessive urinary potassium excretion (Ͼ 30 mmol/day) should prompt further investigations to rule out primary aldosteronism. A ratio of plasma aldosterone (ng/dL) to plasma renin activity (ng/ml/h) level Ͼ 20 suggests the diagnosis.

The aim of treatment is to prevent target organ damage and to decrease cardiovascular mortality. Current practice guidelines stress the importance of blood pressure control. Lower blood pressure treatment thresholds are required in high-risk patients (those with diabetes and target organ damage). Evidence-based use of specific drugs to treat hypertension in special patient groups yields morbidity and mortality benefits, and should be advocated where available and where cost permits. REFERENCES 1.

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